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. 2021 Oct 5;18(10):e1003765. doi: 10.1371/journal.pmed.1003765

Table 5. The network effects of different label types on the perceived disease risk of consuming products.

Outcome Comparison Number of comparisons Direct estimate (RMD and 95% CI) Indirect estimate (RMD and 95% CI) Network estimate (RMD and 95% CI) Proportion of direct evidence
Less healthful products HW vs. control* 10 0.124 (0.053, 0.196) 0.6 (0.153, 1.048) 0.136 (0.065, 0.207) 1.00
HW vs. NW* 2 0.063 (−0.09, 0.215) −0.562 (−0.766, −0.357) −0.16 (−0.283, −0.038) 0.67
HW vs. NW + HW* 1 0.03 (−0.181, 0.241) −0.653 (−1.006, −0.3) −0.15 (−0.331, 0.031) 0.93
NW vs. control* 3 0.43 (0.299, 0.561) −0.304 (−0.582, −0.027) 0.296 (0.178, 0.415) 0.66
NW vs. NW + HW* 1 −0.11 (−0.324, 0.104) 0.463 (0.048, 0.878) 0.01 (−0.18, 0.2) 0.61
NW + HW vs. control 1 0.36 (0.146, 0.574) 0.102 (−0.236, 0.439) 0.286 (0.105, 0.467) 0.23
More healthful products HW vs. control 2 0.024 (0.008, 0.04) . 0.024 (0.008, 0.04) 1.00

RMD refers to the percentage of change comparing intervention with control group (RMD = (x2 − x1) / x1; x1: mean of continuous outcome in the intervention group or after implementation of intervention, x2: mean of continuous outcome in the control group or before implementation of intervention).

*The direct and indirect effects were observed significantly inconsistent (p < 0.05), and the network estimate may violate the assumption of consistency and transitivity of NMA, thus only direct evidence was used for interpretation.

CI, confidence interval; HW, health warning; NMA, network meta-analysis; NS, Nutri-Score; NW, nutrient warning; RMD, relative mean difference; TLS, traffic light labelling system.