. Author manuscript; available in PMC: 2021 Oct 5.

Published in final edited form as: Adapt Med. 2010 Apr 30;2(1):1–10. doi: 10.4247/AM.2010.ABA004

Table 2.

Gene expression in bone marrow after radiation injury and radiation combined injury

Gene	Relative to Sham
Gene	Sham	Wound	RI	CI
p21	1.0	0.4^a	19.7^b	35.9^c
Bax	1.0	0.5^a	8.6^b	17.5^c
Bcl-2	1.0	1.4	1.6	2.0
Bax/Bcl-2	1.0	0.4^a	5.5^b	8.6^c
DDB2	1.0	1.1	5.7^b	7.9^c
Gadd45α	1.0	1.1	5.2^b	4.6^b
TERT	1.0	0.1^a	0.7^b	0.3^c

B6F2D1/J female mice received 8.5 Gy ⁶⁰Co gamma (RI) or 8.5 Gy followed by 15% total body surface area skin wound trauma 1 h after radiation (CI). The skin wound was to remove panniculus carnosus muscle and overlying skin (23.5 ± 1.1 mm in length and 14.9 ± 0.7 mm in width; see ref. 31). Gene expression in bone marrow 24 h after RI or CI was measured using real-time PCR. Each group contained 6 mice.

P < 0.05 vs. Sham, RI, and CI;

P < 0.05 vs. Sham, Wound, and CI;

P < 0.05 vs. Sham, Wound, and RI; determined by Chi-square test.

DDB2: DNA damage-binding protein 2; Gadd45α: Growth arrest and DNA-inducible protein 45α; TERT: Telomerase reverse transcriptase