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. 2021 Sep 21;11:699594. doi: 10.3389/fonc.2021.699594

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Copyright © 2021 Khan, Prajapati, Lakhina, Sharma, Prajapati, Chosdol and Sinha

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gender-based differentially expressed genes in the transcriptomic data [The Cancer Genome Atlas (TCGA)] of glioblastoma multiforme (GBM) in males over females. (A) Dispersion estimate of the count values on performing DeSeq2 analysis. (B) MA Plot showing DeSeq2 result of the differential expression of males over females of TCGA GBM. (C) Graph representing top 20 upregulated genes in males over females and their Log2[fold change (FC)] values in GBM and low-grade glioma (LGG), respectively. (D) Graph representing top 20 downregulated genes in males over females and their Log2(FC) values in GBM 470 *p-value ≤0.05, **p-value ≤0.01, ***p-value ≤0.0001.