Table 1.
Table showing modules having significant differential connectivity of genes in GBM and LGG.
| GBM | ||||
|---|---|---|---|---|
| Module | Size | MeDC | pVal | Top LOC |
| mod1 | 1155 | -1.04143 | >0.0001 | F2RL2, RXRG, LOC101929705 |
| mod9 | 464 | -2.27184 | >0.0001 | SAMD11, LINC01139, MRPL30 |
| mod17 | 176 | -0.46926 | >0.0001 | TSPYL2, GNRHR2, LSM11 |
| mod21 | 200 | -0.84427 | >0.0001 | FOXS1, CD34, ACVRL1 |
| mod25 | 195 | -1.2404 | >0.0001 | CCNB3, CCDC50, EPCAM |
| mod33 | 81 | -0.48983 | >0.0001 | KCNH2, HIST1H2AE, FAM86C2P |
| mod36 | 23 | -1.56159 | >0.0001 | CHODL, CNTNAP3B, RASGRP2 |
| mod48 | 56 | -0.66118 | >0.0001 | TSPAN9, PARP11, OGFRL1 |
| mod52 | 81 | -0.94843 | >0.0001 | TPTEP1, LOC112268292, RASSF3 |
| mod54 | 35 | -1.97712 | >0.0001 | SDCCAG8, CMAS, BLOC1S1-RDH5 |
| mod55 | 60 | -0.33433 | >0.0001 | PLD4, MYBPHL, GTSF1 |
| mod7 | 308 | -1.0111 | 0.02 | LRRC66, CHIC2, DCUN1D4 |
| mod13 | 1092 | -1.67334 | 0.02 | C1QTNF12, COL26A1, SLC16A8 |
| mod20 | 131 | -0.62816 | 0.02 | PCDHB6, ZNF826P, EPCAM-DT |
| mod28 | 132 | -0.93795 | 0.02 | SOX3, ADRA2B, SV2B |
| mod29 | 85 | -1.19756 | 0.02 | ERO1B, MRPS16, DNAJC1 |
| mod32 | 124 | -0.86194 | 0.02 | ACY3, C1orf115, HLA-A |
| mod37 | 44 | -2.38596 | 0.02 | HELB, CASC4 |
| mod40 | 64 | -0.7144 | 0.02 | LGALS2, IPO9-AS1, MYBPH |
| mod35 | 109 | -0.42696 | 0.04 | LINC01206, PTPRG-AS1, FAM13B |
| mod39 | 29 | -1.61494 | 0.04 | EYS, LIMS2, BCAS1 |
| mod44 | 27 | -0.42343 | 0.04 | CPM |
| LGG | ||||
| Module | Size | MeDC | pVal | Top LOC |
| mod18 | 351 | -0.11011 | 0 | USP9Y, CTRB1, MIR2052HG |
| mod34 | 125 | -0.11337 | 0 | RPS15AP29, LINC01098, DNAJB6P8 |
| mod46 | 70 | -0.15036 | 0 | HSFY2, NIFKP3, LOC100419861 |
| mod13 | 634 | -0.10115 | 0.02 | LOC339260, DNM1P46, LOC101929577 |
| mod16 | 493 | -0.09839 | 0.02 | DDX3Y, RPL10P1, PNPLA1 |
| mod22 | 287 | -0.08038 | 0.02 | MAJIN, LINC01606, PPIAP51 |
| mod42 | 81 | -0.1127 | 0.02 | CAB39P1, ANKRD44-AS1 |
| mod43 | 79 | -0.12776 | 0.02 | SEPHS1P2, RNU6-606P, LOC100996263 |
| mod11 | 770 | -0.0992 | 0.04 | CT66, LINC01480, LRRC69 |
| mod12 | 726 | -0.10386 | 0.04 | PAX8-AS1, PAX8, KRTAP5-10 |
| mod19 | 344 | -0.09355 | 0.04 | LINC01305, POU2F3, RNU4-62P |
| mod14 | 560 | -0.10249 | 0.06 | RPL31P49,KRT8P46, TULP2 |
| mod21 | 311 | -0.06843 | 0.06 | GCM1, LOC105372316, FLJ40194 |
| mod25 | 214 | -0.10412 | 0.06 | BCORP1, LOC101928401, LOC339966 |
| mod53 | 38 | -0.13482 | 0.06 | RNF113B |
GBM, glioblastoma multiforme; LGG, low-grade glioma; LOC, loss of connectivity; MeDC, mean differential connectivity.