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. 1999 Jun;37(6):1676–1682. doi: 10.1128/jcm.37.6.1676-1682.1999

TABLE 2.

Published MICs of antimicrobial agents for M. abscessus, M. chelonae, and the M. fortuitum group with Mueller-Hinton agar or brotha

Drug M. abscessus
M. chelonae
M. fortuitum group
MIC range Mode MIC range Mode MIC range Mode
Amikacin 4–32 (93) 812 4–32 (88) 1612 ≤1–2 (96) ≤112
Tobramycin 1–4 (100)12 112
Sulfamethoxazole ≥64 (100) >6412 ≥64 (97) >6412 ≤32 (95) ≤412
Cefoxitin 16–64 (94) 3212 >64 (98) >6412 16–64 (97) 3212
Imipenem 4–32 (90) 1611 4–32 (89) 1614 ≤1–8 (99) 49, 14
Doxycycline >16 (96) >1612 0.25–1.0 (26) <0.512 <0.25–1.0 (40) <0.512
≥16 (74) ≥1612 ≥16 (44) ≥1612
Clarithromycin ≤0.25–2.0 (100) 0.1254 ≤0.25–1.0 (100) 0.1254 0.25–4 (81) 24
8–>8 (19) >84
Ciprofloxacin 1–2 (6) 213 1–2 (19) 213 <0.25–1.0 (98) <0.0639, 13
4–>8 (94) >813 4–>8 (81) >813
a

Summarized from references 4, 9, and 12 to 14. The percentage of strains within each given range is listed in parentheses. The superscript indicates the reference number.