TABLE 3.
MICs of seven antimicrobial agents for M. abscessus reported by four laboratories
| Drug | MIC (μg/ml) for isolatea:
|
|||||
|---|---|---|---|---|---|---|
| 1801
|
1802
|
1807
|
||||
| Mode (range) | % Agreement | Mode (range) | % Agreement | Mode (range) | % Agreement | |
| Amikacin | 16 (8–64) | 97.2 | 32 (16–64) | 100 | 16 (8–32) | 100 |
| Cefoxitin | 32 (8–64) | 100 | 64 (8–512) | 97.2 | 32 (16–32) | 100 |
| Ciprofloxacin | 16 (4–32) | 91.7 | 32 (16–32) | 100 | 32 (16–32) | 100 |
| Clarithromycin | 0.5 (0.03–4) | 47.2 | 128 (128) | 100 | 0.25 (0.125–0.5) | 100 |
| Doxycycline | 64 (32–64) | 100 | 64 (16–64) | 97.2 | 64 (64) | 100 |
| Imipenem | 8 (4–128) | 75.0 | 16 (8–32) | 100 | 8 (8–128) | 86.1 |
| Sulfamethoxazole | 128 (16–128) | 97.2 | 128 (128) | 100 | 128 (128) | 100 |
a
% Agreement, percentage of MICs in each three-dilution range (mode ± log2). High off-scale MICs were converted to the next-highest concentration; low off-scale MICs were left unchanged.