TABLE 4.
MICs of eight antimicrobial agents for M. chelonae reported by four laboratories
| Drug | MIC (μg/ml) for isolatea:
|
|||||
|---|---|---|---|---|---|---|
| 1814
|
1831
|
1866
|
||||
| Mode (range) | % Agreement | Mode (range) | % Agreement | Mode (range) | % Agreement | |
| Amikacin | 128 (32–256) | 97.2 | 64 (8–128) | 66.7 | 32 (8–64) | 80.5 |
| Cefoxitin | 512 (512) | 100 | 512 (256–512) | 100 | 512 (256–512) | 100 |
| Ciprofloxacin | 32 (2–32) | 66.7 | 8 (2–32) | 77.8 | 16 (2–32) | 94.4 |
| Clarithromycin | 0.125 (0.06–0.25) | 100 | 0.25 (0.03–0.5) | 88.9 | 128 (8–128) | 97.2 |
| Doxycycline | 0.25 (0.25–2) | 61.1 | 64 (32–64) | 100 | 64 (64) | 100 |
| Imipenem | 16 (4–128) | 88.9 | 16 (4–64) | 86.1 | 32 (8–128) | 75.0 |
| Sulfamethoxazole | 128 (32–128) | 91.7 | 128 (32–128) | 97.2 | 128 (32–128) | 97.2 |
| Tobramycin | 8 (4–32) | 77.8 | 2 (1–8) | 94.4 | 2 (1–4) | 100 |
a
% Agreement, percentage of MICs in each three-dilution range (mode ± log2). High off-scale MICs were converted to the next-highest concentration; low off-scale MICs were left unchanged.