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. Author manuscript; available in PMC: 2021 Oct 5.
Published in final edited form as: Med. 2021 Sep 10;2(9):1011–1026. doi: 10.1016/j.medj.2021.08.005

Figure 1: Organoids derived from healthy and diseased tissue can be used to model various aspects of human physiology.

Figure 1:

These include (clockwise from top left) modelling mutational cascades involved in carcinogenesis, features of pathogenic viral and bacterial infections, capturing the heterogeneity of tumor genetic subtypes, and cell-cell interactions that promote malignant cellular characteristics.