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(A) Auxin treatment extended lifespan in aged DAF-2::degron animals. Animals were shifted from DMSO plates to plates containing 1 mM auxin on the indicated day. (B–D) Top-coating of plates with auxin to a final concentration of 1 mM, at the indicated days, extended the lifespan of DAF-2::degron animals during aging. For (A–D), see Supplementary file 1 and Source data 1 for raw data, statistics, and additional independent trials.
