Figure 2.

Cell-associated unspliced human immunodeficiency virus (HIV) RNA during immune checkpoint blockade (ICB). The level of cell-associated unspliced HIV RNA during ICB shown in absolute numbers and as fold-changes from baseline for the entire cohort (A and B) and for groups receiving nivolumab alone (C) or nivolumab plus ipilimumab (D). Data points are connected for the same participant receiving nivolumab plus ipilimumab in cycle 1 (E) and cycle 4 (F). G, Fold-changes from baseline are displayed and compared across groups receiving nivolumab or nivolumab plus ipilimumab. Abbreviations: CA-US, cell-associated unspliced; FC, fold-change; HIV, human immunodeficiency virus; ICB, immune checkpoint blockade; Ipi, ipilimumab; Nivo, nivolumab.