Table 3. Comparison between different weight-reducing bariatric surgical interventions based on %TBWL, NAS, and NFS improvement and the incidence rate of adverse events.
Surgical intervention | Procedure | Mean %TBWL | NAS improvement | NFS improvement | Adverse event (%) |
---|---|---|---|---|---|
Sleeve gastrectomy | A restrictive bariatric procedure that involves resection of two-thirds of the stomach's greater curvature and gastric fundus creating a long tubular gastric conduit running along the lesser curvature. 76 | −31.7% after 6 mo. 84 | −2.3 NAS score improvement. 81 | Significant reduction in NFS of −0.7. 81 | Nutritional deficiencies (7.4–30.5%). Nondysplastic Barrett's esophagus (15.16%) Choledocholithiasis (5.15%) Cholecystectomy (3%). 87 |
Roux-en-Y gastric bypass | A reconstructive procedure performed by connecting a limb of the small intestine to a small gastric pouch forming a shape of “ Y .” Bypassing a portion of the large stomach pouch and proximal small intestine reduces the amount of nutrients and calories being absorbed. 77 | −34.6% after 6 mo. 84 |
Improvement or complete resolution of steatosis, steatohepatitis by 91 and 60%, respectively.
78
−2.8 NAS score improvement. 79 |
31% improvement in NFS
78
−1.0 reduction in NFS score. 79 |
Cholelithiasis (32–42%) Nutritional deficiencies (30–35%) Dumping syndrome (13%) Gastro-gastric fistula (1–2%) Small bowel obstruction (1.5–5%). 88 |
Abbreviations: NAS, nonalcoholic fatty liver disease activity score; NFS, nonalcoholic fatty liver disease fibrosis score; TBWL, total body weight loss.