Table 3.
Unadjusted and Adjusted Multivariable Linear Regression of Factors Associated With IL-1β
| Unadjusted | Adjusted | |||
|---|---|---|---|---|
| β-Coefficient (95% CI) | P | β-Coefficient (95% CI) | P | |
| HIV status | .27 (.06, .47) | .010 | .30 (.07, .52) | .011 |
| Age (years) | ||||
| 30–39 | Reference | Reference | ||
| 40–49 | .24 (−.11, .49) | .061 | .10 (−.17, .37) | .473 |
| 50–59 | .03 (−.25, .31) | .837 | −.11 (−.42, .20) | .487 |
| ≥60 | .04 (−.29, .38) | .796 | −.06 (−.42, .30) | .746 |
| Sex | ||||
| Female | Reference | Reference | ||
| Male | .32 (.13, .53) | .002 | .37 (.13, .60) | .002 |
| BMI (kg/m2) | ||||
| Normal (18–24) | Reference | Reference | ||
| Underweight (<18) | −.16 (−.52, .20) | .379 | −.26 (−.61, .11) | .175 |
| Overweight (25–29) | −.27 (−.53, −.01) | .039 | −.10 (−.37, .17) | .469 |
| Obese (≥30) | .12 (−.18, .42) | .429 | .36 (.04, .69) | .030 |
| Current smoker | .18 (−.18, .42) | .459 | .08 (−.41, .57) | .741 |
| Alcohol use in past 12 months | .13 (−.13, .39) | .322 | .01 (−.28, .28) | .984 |
| Hypertension | −.13 (−.38, .12) | .306 | .11 (−.14, .38) | .373 |
| Diabetes | .01 (−.46, .48) | .964 | .03 (−.44, .51) | .887 |
| LDL cholesterol >130 mg/dL | −.34 (−.64, −.05) | .024 | −.42 (−.96, .11) | .120 |
| HDL cholesterol <50 mg/dL for males and <40 mg/dL for females | −.15 (−.37, .71) | .183 | −.08 (−.32, .16) | .526 |
| Total cholesterol >200 mg/dL | −.21 (−.48, .07) | .139 | .04 (−.46, .54) | .871 |
| Triglycerides >150 mg/dL | −.01 (−.38, .36) | .969 | −.13 (−.52, .27) | .524 |
Abbreviations: BMI, body mass index; CI, confidence interval; HDL, high-density lipoprotein; HIV, human immunodeficiency virus; IL-1β, interleukin 1β; LDL, low-density lipoprotein.