Table 4.
Unadjusted and Adjusted Multivariable Linear Regression of Factors Associated With IL-6
| Unadjusted | Adjusted | |||
|---|---|---|---|---|
| β-Coefficient (95% CI) | P | β-Coefficient (95% CI) | P | |
| HIV status | .38 (.19, .56) | <.001 | .41 (.21, .61) | <.001 |
| Age (years) | ||||
| 30–39 | Reference | Reference | ||
| 40–49 | .33 (.10, .56) | .005 | .17 (−.06, .42) | .163 |
| 50–59 | .48 (.23, .73) | <.001 | .28 (−.01, .55) | .051 |
| ≥60 | .71 (.41, 1.01) | <.001 | .59 (.27, .92) | <.001 |
| Sex | ||||
| Female | Reference | Reference | ||
| Male | .36 (.18, .55) | <.001 | .34 (.13, .55) | .001 |
| BMI (kg/m2) | ||||
| Normal (18–24) | Reference | Reference | ||
| Underweight (<18) | −.16 (−.50, .18) | .355 | −.22 (−.55, .10) | .183 |
| Overweight (25–29) | −.24 (−.50, −.18) | .048 | −.10 (.35, .14) | .406 |
| Obese (≥30) | .10 (−.19, .38) | .505 | .27 (−.04, .58) | .083 |
| Current smoker | .35 (−.09, .79) | .117 | .19 (−.26, .63) | .410 |
| Alcohol use in past 12 months | .17 (−.07, .42) | .162 | .17 (−.87, .42) | .198 |
| Hypertension | −.15 (−.07, .38) | .194 | .08 (−.15, .31) | .501 |
| Diabetes | −.31 (−.74, .12) | .158 | −.33 (−.75, .10) | .129 |
| LDL cholesterol >130 mg/dL | −.13 (−.15, −.41) | .355 | −.01 (−.49, .46) | .962 |
| HDL cholesterol <50 mg/dL for males and <40 mg/dL for females | −.05 (−.16, .25) | .660 | .24 (−.02, .45) | .031 |
| Total cholesterol >200 mg/dL | .16 (−.08, .42) | .191 | .08 (−.36, .52) | .729 |
| Triglycerides >150 mg/dL | .21 (−.13, .55) | .225 | −.01 (−.36, .34) | .973 |
Abbreviations: BMI, body mass index; CI, confidence interval; HDL, high-density lipoprotein; HIV, human immunodeficiency virus; IL-6, interleukin 6; LDL, low-density lipoprotein.