Table 5.
Unadjusted and Adjusted Multivariable Linear Regression of Factors Associated With TNF-α
| Unadjusted | Adjusted | |||
|---|---|---|---|---|
| β-Coefficient (95% CI) | P | β-Coefficient (95% CI) | P | |
| HIV status | .37 (.20, .53) | <.001 | .34 (.16, .52) | <.001 |
| Age (years) | ||||
| 30–39 | Reference | Reference | ||
| 40–49 | .33 (.12, .54) | .002 | .22 (−.01, .45) | .052 |
| 50–59 | .38 (.15, .60) | .001 | .23 (−.02, .48) | .073 |
| ≥60 | .50 (−.23, .77) | <.001 | .42 (.13, .71) | .005 |
| Sex | ||||
| Female | Reference | Reference | ||
| Male | .31 (.14, .48) | <.001 | .27 (.08, −.46) | .005 |
| BMI (kg/m2) | ||||
| Normal (18–24) | Reference | Reference | ||
| Underweight (<18) | −.19 (−.50, .11) | .210 | −.26 (−.55, .04) | .088 |
| Overweight (25–29) | −.18 (−.39, .04) | .119 | −.05 (−.27, .17) | .671 |
| Obese (≥30) | −.19 (−.45, .07) | .144 | −.06 (−.34, .22) | .646 |
| Current smoker | .13 (−.26, .52) | .506 | −.02 (−.42, .39) | .927 |
| Alcohol use in past 12 months | .12 (−.10, .33) | .289 | .12 (−.11, .35) | .306 |
| Hypertension | .03 (−.17, .24) | .745 | .10 (−.11, .31) | .873 |
| Diabetes | −.37 (−.76, .02) | .063 | −.43 (−.84, −.03) | .045 |
| LDL cholesterol >130 mg/dL | .02 (−.23, .27) | .894 | −.20 (−.63, .23) | .359 |
| HDL cholesterol <50 mg/dL for males and <40 mg/dL for females | .01 (−.18, .19) | .938 | .16 (−.04, .35) | .110 |
| Total cholesterol >200 mg/dL | .11 (−.11, .34) | .326 | .20 (−.20, .60) | .319 |
| Triglycerides >150 mg/dL | .15 (−.15, .45) | .336 | −.02 (−.34, .30) | .893 |
Abbreviations: BMI, body mass index; CI, confidence interval; HDL, high-density lipoprotein; HIV, human immunodeficiency virus; LDL, low-density lipoprotein; TNF-α, tumor necrosis factor α.