Table 3.

Cases With Negative Blood Culture and Positive 16S Ribosomal RNA Gene Polymerase Chain Reaction Followed by Next-Generation Sequencing Results

16S rRNA Gene NGS Results	Clinical Syndrome
Fusobacterium periodonticum	Cholecystitis
Enterobacterales	Abdominal abscess
Streptococcus species	Neutropenic fever
Clostridium saudiense	Pancolitis
Bacteroides vulgatus	Clostridioides difficile colitis
Prevotella bivia	C. difficile colitis, pneumonia
Legionella pneumophila	Legionella pneumophila serotype 1 pneumonia
Streptococcus agalactiae, Enterobacter cloacae, Streptococcus salivarius, Staphylococcus lugdunensis	Diabetic foot infection
Fusobacterium nucleatum	Pneumonia
F. nucleatum, Capnocytophaga species	Necrotizing pneumonia
Enterobacterales	Pneumonia with cystic fibrosis exacerbation
Enterobacterales	Pneumonia
Stenotrophomonas maltophilia	Pneumonia
S. maltophilia	Pneumonia
Acidovorax species	Newly diagnosed acute myelogenous leukemia, fever with functional neutropenia
Clostridium species
Enterobacterales	Cardiogenic shock
Enterobacterales	Probable septic arthritis

Abbreviations: NGS, next-generation sequencing; rRNA, ribosomal RNA.