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. 2021 Sep 22;6(18):e148003. doi: 10.1172/jci.insight.148003

Figure 4. Drug treatment reduces viral titer in lung microtissues.

Figure 4

(A–F) The percentage inhibition in viral titer for 6 different drugs in 5 different donors and the Vero E6 cell line. For DMSO-soluble drugs (remdesivir and sirolimus), the percentage inhibition was calculated using infected samples treated with an equivalent amount of DMSO. Significance was determined using a 2-way ANOVA to test for interaction between individual donors and the dose of drug. Three technical replicates were analyzed for each donor and treatment. *P < 0.05; **P < 0.01.