Skip to main content
. 2021 Sep 8;6(17):e132585. doi: 10.1172/jci.insight.132585

Figure 2. Acute pancreatitis was induced by CNO in hM3/BAC mice.

Figure 2

(A) Tamoxifen (50 mg/kg; oral gavage) was administered on1e week prior to CNO (6 mg/kg; ip). Mice were sacrificed 24 hours after the CNO injection. (B) Pancreas edema (pancreas/body weight ratio, mg/g) and serum amylase were measured (n ≥ 8 mice/group). Mean ± SEM (n = 8). (C) HE staining and immunohistochemical (IHC) analysis of pancreatic tissues (scale bar: 200 μm). (D) Quantification of the necrotic cells. Mean ± SEM (n = 8). (E) Quantification of the inflammatory cells. Mean ± SEM (n = 8). *P 0.05, hM3/BAC vs. BAC group. #P 0.05, hM3/BAC group vs. hM4/BAC group. Two-way ANOVA with Tukey’s test.