Table 5. Summary of adverse drug reactions.
| System organ class (preferred term) | Treatment | ||||
|---|---|---|---|---|---|
| 100 BID (n = 10) | 200 QD (n = 10) | 200 BID (n = 10) | R40 BID (n = 10) | ||
| Gastrointestinal disorders | |||||
| Dyspepsia | 1 (10.0) | 1 (10.0) | |||
| Diarrhea | 1 (10.0) | ||||
| Nervous system disorders | |||||
| Headache | 1 (10.0) | ||||
| Infection and infestations | |||||
| Nasopharyngitis | 1 (10.0) | ||||
| Folliculits | 1 (10.0) | ||||
| Investigations | |||||
| Body temperature increased | 1 (10.0) | ||||
Values are presented as number (%).
100 BID, YH4808 100 mg twice a day for 14 days; 200 QD, YH4808 200 mg once a day for 14 days; 200 BID, YH4808 200 mg twice a day for 14 days; R40 BID, esomeprazole 40 mg twice a day for 14 days.