Table 1.
Univariate analysis of overall survival of patients (n = 141) with pseudomyxoma peritonei.
| Index | n (%) | Median overall survival, months | 95% confidence interval | Statistical analysesa |
|---|---|---|---|---|
| Histological grade | P < 0.001 | |||
| LGMC | 93 (66.0) | 86.0 | 58.184, 113.816 | |
| HGMC | 43 (30.5) | 44.7 | 37.516, 51.884 | |
| HGMC-S | 5 (3.5) | 11.4 | 4.834, 17.966 | |
| CEA | NS | |||
| Positive | 135 (95.7) | 72.8 | 77.842, 138.056 | |
| Negative | 6 (4.3) | 127.3 | 38.249, 137.927 | |
| Ki67 LI | P < 0.001 | |||
| <50% | 95 (67.4) | 86.0 | 41.741, 130.258 | |
| ≥50% | 46 (32.6) | 44.7 | 23.753, 65.647 | |
| p53 | P = 0.001 | |||
| Normal | 94 (66.7) | 86.0 | 66.650, 105.350 | |
| Aberrant | 47 (33.3) | 45.7 | 38.545, 52.915 | |
| Lymph node involvement | P < 0.001 | |||
| Absent | 131 (92.9) | 83.0 | 59.567, 106.433 | |
| Present | 10 (7.1） | 20.0 | 17.434, 22.566 | |
| Angiolymphatic invasion | P < 0.001 | |||
| Absent | 130 (92.2) | 83.0 | 59.913, 106.087 | |
| Present | 11 (7.8) | 40.0 | 0.367, 79.633 | |
| Perineural invasion | NS | |||
| Absent | 137 (97.2) | 83.0 | 54.024, 111.976 | |
| Present | 4 (2.8) | 56.9 | – |
LGMC, low-grade mucinous carcinoma; HGMC, high-grade mucinous carcinoma; HGMC-S, high-grade with signet ring cells; CEA, carcinoembryonic antigen; LI, labelling index; NS, no significant association (P ≥ 0.05).