Table 1.

Demographics and clinical characteristics of HPV-associated and smoking-associated HNSCC groups

		HPV-associated (n=55)		Smoking-associated (n=82)		P value
Death*	reported death	4	8%	24	34%
	living/censored	47	92%	47	66%
Survival time (months)	mean (sd)	46.3	17.8	37.3	20.6	0.01
Age (years)	mean (sd)	56.8	7.8	60.1	10.5	0.05
BMI (kg/m2)	mean (sd)	29.0	4.7	26.1	5.3	0.001
Sex	Men	49	89%	51	62%	<0.001
	Women	6	11%	31	38%
Race	white	48	87%	59	72%	0.03
	All others	7	13%	23	28%
Alcohol use*	<1 drink per wk	28	52%	49	60%	0.32
	>=1 drink per wk	26	48%	32	40%
Tumor site	Oropharynx	53	96%	12	15%	<0.001
	All others	2	4%	70	85%
Tumor Stage*	I–III	38	70%	29	41%	<0.001
	IV	16	30%	52	59%
ECOG status*	0 (fully active)	39	74%	24	32%	<0.001
	1 (restricted)	13	25%	38	50%
	2 (unable to work)	1	2%	14	18%
Treatment	Radiotherapy only	10	18%	17	21%	0.43
	Chemoradiotherapy	45	82%	65	79%

HPV=human papillomavirus; HNSCC=head and neck squamous cell carcinoma; sd=standard deviation; IQR=interquartile range;

^*indicates a variable that was missing in ≥1 subject.