Figure 1:
Sequence similarity between randomly chosen antibody sequences from the HIP database and our template database of human co-crystal structures. Over 4 million antibody heavy chains and almost 2 million antibody light chains were tested using a BLAST search and their highest percentage match was recorded for each CDR individually and binned in steps of 5 percent. A. distribution of template similarity for heavy chain CDRs. B. Distribution of template similarity for light chain CDRs.