Table 1:

Median backbone and HCDR3 RMSDs by method for each antibody tested from the benchmark set.

PDB	Median Backbone RMSD to Native Crystal Structure of the Top 10 of Models by Energy Score			Median HCDR3 RMSD to Native Crystal Structure of the Top 10 of Models by Energy Score			HCDR3 Sequence Identity to the Closest HCDR3 Template	HCDR3 Length
	Multi-Template	Rosetta Antibody	AbPredict	Multi-Template	Rosetta Antibody	AbPredict
1ADQ	1.25	2.41	x†	3.99	x	x	0.36	14
1AFV	1.42	1.46	0.84	3.15	4.54	1.65	0.55	11
1EGJ	0.99	1.18	0.81	2.20	5.21	2.77	0.40	10
1EO8	1.44	1.49	1.99	4.09	4.45	6.22	0.44	9
1HEZ	0.85	1.25	1.01	1.60	8.52	3.53	0.25	12
1I9R	1.15	1.19	1.12	2.01	4.63	5.23	0.33	9
1IQD	1.15	1.38	2.60	1.72	4.17	4.73	0.38	8
1KB5	1.06	x	0.95	2.30	x	2.62	0.60	10
1KEN	1.89	1.79	1.90	5.22	6.00	3.92	0.45	11
1NCB	1.43	1.08	x	3.31	4.10	x	0.36	11
1NMB	1.66	1.72	0.94	3.10	6.69	5.74	0.31	13
1NSN	1.30	1.31	x	2.62	2.33	x	0.75	4
1OB1	1.23	1.55	2.62	3.66	4.87	8.01	0.36	11
1ORQ	1.36	1.17	1.58	1.79	2.75	3.22	0.56	9
1OSP	1.79	1.33	1.68	3.07	4.55	5.20	0.33	12
1QFU	1.37	2.27	0.84	4.23	9.00	4.94	0.31	13
1RJL	1.09	1.23	0.95	4.55	4.05	3.81	0.27	11
1YJD	1.15	1.46	0.87	3.05	4.29	4.39	0.45	11
1YQV	1.49	1.31	x	5.47	4.53	x	0.57	7
1ZTX	1.18	1.26	3.65	1.58	5.13	9.69	0.40	10
2ADF	1.07	1.26	0.98	2.44	2.84	3.26	0.44	9
2ARJ	0.92	1.53	x	1.83	4.19	x	0.56	9
2HMI	1.29	1.26	1.88	3.62	5.22	6.29	0.31	13
2I9L	0.93	1.56	0.68	2.21	5.79	3.25	0.20	10
2JEL	1.01	1.22	0.99	2.39	2.29	3.46	0.33	9
2NYY	0.99	1.25	1.41	1.99	3.41	5.37	0.56	9
2NZ9	0.96	1.05	1.11	2.07	3.09	3.14	0.22	9
2Q8B	1.09	x	x	2.45	x	x	0.33	3
2QR0	1.25	1.73	1.16	1.75	6.01	2.62	0.67	9
2R29	1.17	1.48	x	1.68	3.32	x	0.57	7
2R56	0.96	1.73	0.96	1.31	8.67	5.67	0.42	12
2XRA	1.71	2.21	1.65	4.01	7.23	4.29	0.38	13
2YPV	1.22	1.09	0.72	3.33	5.18	4.75	0.60	10
2ZCH	1.25	1.30	x	3.49	7.68	x	0.46	13
2ZUQ	1.06	1.85	0.83	2.09	3.42	4.14	0.67	6
3B9K	1.19	2.11	1.04	2.54	3.84	2.56	0.67	9
3BGF	1.09	1.32	3.54	3.67	4.88	8.56	0.25	12
3D85	0.97	1.22	1.04	3.02	3.72	3.91	0.33	6
3EFF	1.45	2.11	1.78	4.18	8.23	5.88	0.53	15
3FMG	1.17	1.09	1.00	3.49	3.55	3.82	0.42	12
3KS0	1.69	1.71	x	2.13	3.24	x	0.56	9
3LIZ	1.24	1.30	0.93	4.83	4.20	5.24	0.40	10
3OPZ	1.11	1.36	1.02	2.74	3.66	3.38	0.50	10
3Q3G	1.50	1.77	1.01	4.39	9.42	4.46	0.15	13
3R1G	1.03	1.44	1.13	1.96	3.69	2.90	0.50	10
3RKD	1.06	x	1.61	2.81	x	5.43	0.36	14
3UBX	1.32	1.18	1.05	4.15	6.20	6.28	0.18	11
3V7A	1.28	1.48	1.08	2.55	4.39	3.82	0.45	11
3VG9	1.59	1.81	x	7.54	5.37	x	0.47	15
3VRL	1.27	1.70	1.12	4.15	7.59	4.45	0.62	13
3WFD	1.05	x	0.94	2.08	x	7.24	0.40	15
4AG4	1.25	1.70	0.84	1.61	3.56	5.08	0.71	7
4BZ1	0.77	1.19	0.84	1.41	2.74	3.70	0.38	8
4BZ2	1.34	1.32	0.83	5.25	4.01	5.92	0.58	12
4CAD	1.41	x	0.85	6.98	x	6.21	0.38	16
4CMH	1.07	1.35	1.25	2.44	6.08	3.71	0.36	11
4FFV	1.17	1.10	3.58	1.92	2.30	11.34	0.38	8
4H88	0.96	0.99	0.81	1.79	6.34	3.16	0.60	10
4HT1	1.54	2.01	1.83	1.48	4.45	5.01	0.36	11
4JR9	1.03	2.16	0.81	3.20	2.98	4.12	0.11	9
4JZJ	1.49	1.41	0.92	3.24	6.76	4.25	0.36	11
4K2U	1.07	1.18	0.92	2.47	5.92	3.97	0.42	12
4LVN	1.60	1.13	1.24	4.95	3.89	3.26	0.45	11
4NP4	1.23	1.79	1.29	2.23	8.28	3.45	0.40	10
4PLJ	1.28	x	1.00	3.30	x	5.56	0.57	14
4Q6I	1.26	1.49	x	4.98	6.16	x	0.45	11
4QWW	1.08	1.19	x	5.41	7.01	x	0.50	14
4RDQ	0.92	x	1.13	0.85	x	4.30	0.57	7
4RGM	1.31	1.50	1.16	5.48	4.68	4.70	0.33	12
4RGO	1.26	1.67	0.81	4.45	8.45	5.67	0.42	12
4TNW	2.09	1.77	x	4.19	5.33	x	0.62	13
4UAO	1.16	1.13	1.09	5.01	8.18	4.28	0.33	12
4ZPT	1.06	0.94	1.20	1.80	2.48	4.78	0.57	7
5BV7	1.65	x	2.07	6.42	x	7.83	0.38	16
5CZX	1.27	1.77	0.91	2.82	3.36	3.44	0.50	10
5DFV	0.93	1.62	1.89	2.72	5.22	4.05	0.33	12
5HBT	1.61	3.41	1.49	2.91	x	5.78	0.25	12
5KVF	1.10	1.42	0.88	7.60	5.12	6.00	0.20	10
5LQB	0.98	1.14	x	3.00	4.08	x	0.33	12
5MHR	1.81	1.84	1.32	2.78	3.69	4.86	0.50	12
5T5F	1.40	1.97	1.18	4.23	6.63	4.92	0.38	13
5USH	1.21	1.87	2.17	2.28	10.10	6.48	0.31	13
5USL	1.84	2.02	3.94	7.28	7.59	10.92	0.27	15
5VEB	0.94	1.41	0.98	1.64	5.21	3.78	0.44	9
5Y9C	1.33	1.44	1.57	3.02	4.41	3.75	0.45	11
5Y9F	1.31	1.52	1.08	3.30	7.86	4.27	0.29	14
6BPA	1.14	1.18	1.01	2.27	4.30	3.08	0.18	11

^†X indicates a failure by the method represented to produce any models of sufficient quality