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. 2021 Oct 5;11:19717. doi: 10.1038/s41598-021-99201-3

Table 1.

Clinical characteristics according to the TMT measurement.

No. (%) TMT on CT (mm) P value
 > 6.24 mm  ≤ 6.24 mm
No. (%) 106 (100%) 53 (50%) 53 (50%) NA
Mean age (years) 68.8 ± 2.8 64.1 ± 0.8 0.038*
Sex
Men 84 (79.2%) 38 (71.7%) 46 (86.8%) 0.056
Women 22 (20.8%) 15 (28.3%) 7 (13.2%)
Smoking status
Never smoked 56 (52.8%) 31 (58.5%) 25 (47.2%) 0.195
Former smoker 26 (24.5%) 9 (17.0%) 17 (32.1%)
Current smoker 24 (22.6%) 13 (24.5%) 11 (20.8%)
Treatment modality
Initial surgery 13 (12.3%) 7 (13.2%) 6 (11.3%) 0.739
Surgery after neoadjuvant chemoradiation 37 (34.9%) 20 (37.7 5) 17 (32.1%)
Adjuvant radiation or chemoradiation 37 (34.9%) 20 (37.7 5) 17 (32.1%)
Human papillomavirus
Negative 79 (74.5%) 41 (77.4%) 38 (71.7%) 0.505
Positive 27 (25.5%) 12 (22.6%) 15 (28.3%)
Tumor site
Sinonasal cavity 8 (7.5%) 5 (9.4%) 3 (5.7%) 0.944
Oral cavity 17 (16.0%) 9 (17.0%) 8 (15.1%)
Nasopharynx 14 (13.2%) 6 (11.3%) 8 (15.1%)
Oropharynx 33 (31.1%) 17 (32.1%) 16 (30.2%)
Hypopharynx 12 (11.3%) 5 (9.4%) 7 (13.2%)
Larynx 22 (20.8%) 11 (20.8%) 11 (20.8%)
cT category
T1 16 (15.1%) 5 (9.4%) 11 (20.8%) 0.103
T2 31 (29.2%) 13 (24.5%) 18 (34.0%)
T3 27 (25.5%) 18 (34.0%) 9 (17.0%)
T4 32 (30.2%) 17 (32.1%) 15 (28.3%)
cN category
N0 43 (40.6%) 22 (41.5%) 21 (39.6%) 0.749
N1 25 (23.6%) 12 (22.6%) 13 (24.5%)
N2 27 (25.5%) 12 (22.6%) 15 (28.3%)
N3 11 (10.4%) 7 (13.2%) 4 (7.5%)
cM category
M0 53 (50.0%) 48 (48.5%) 5 (71.4%) 0.243
M1 53 (50.0%) 51 (51.5%) 2 (28.6%)
Overall stage
I 18 (17.0%) 6 (11.3%) 12 (22.6%) 0.383
II 20 (18.9%) 10 (18.9%) 10 (18.9%)
III 34 (32.1%) 17 (32.1%) 17 (32.1%)
IV 34 (32.1%) 20 (37.7%) 14 (26.4%)
Preoperative serum albumin (g/dL) 4.19 ± 0.47 4.04 ± 0.56 0.134

The patients were dichotomized according to the median TMT value.

TMT temporalis muscle thickness, cT clinical tumor, cN clinical node, cM clinical metastasis, NA not applicable.

*P value less than 0.05 indicates statistical significance.