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. 2021 Oct 5;11:19712. doi: 10.1038/s41598-021-99311-y

Table 1.

Patient characteristics.

N (%) or median(range)
Total 128 (100)
Age 62 (21–82) years
Sex
Male 89 (69.5)
Female 39 (30.5)
ECOG PS
0 27 (21.1)
1 98 (76.6)
2 1 (0.8)
Unknown 2 (1.6)
Diagnosis
NSCLC 50 (39.1)
Melanoma 31 (24.2)
SCLC 14 (10.9)
UCC 13 (10.2)
RCC 6 (4.7)
HNSCC 5 (3.9)
Salivary gland cancer 4 (5.8)
Others 5 (3.9)
History of radiotherapy*
Never irradiated 50 (39.1)
Received radiotherapy 78 (60.9)
 Within 4 weeks to ICI treatment 14 (17.9)
 Earlier than 4 weeks 43 (55.1)
 After end of ICI treatment 21 (26.9)
Type of ICI treated
Monotherapy
 Nivolumab 41 (32.0)
 Pembrolizumab 32 (25.0)
 Durvalumab 15 (11.7)
 Ipilimumab 5 (3.9)
 Atezolizumab 4 (3.1)
Combination therapy
 Pembrolizumab/other 13 (10.2)
 Atezolizumab/other 13 (10.2)
 Nivolumab and ipilimumab 2 (1.6)
Others 3 (2.3)

ECOG PS eastern cooperative oncology group performance status, NSCLC non-small cell lung cancer, SCLC small cell lung cancer, UCC urothelial carcinoma, RCC renal cell carcinoma, HNSCC head and neck squamous cell carcinoma, ICI immune checkpoint inhibitor.

*Encompasses all types of radiotherapy, including stereotactic radiosurgery.

Denotes patients who received ICI as part of a clinical trial.