Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 21;53(9):1379–1389. doi: 10.1038/s12276-021-00671-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — a t-SNE plot of the EC subpopulations (EC_1, EC_2, and EC_3) from the ND (336 cells) and HFD (521 cells) groups. b Percentages of the EC subpopulations in the ND (EC_1, 49%; EC_2, 28%; and EC_3, 23%) and HFD (EC_1, 60%; EC_2, 23%; and EC_3, 17%) groups. c Heatmap of the top 10 marker genes per subpopulation. d Violin plots of signature genes confirming the subpopulation identities. e–g Top 10 pathways associated with the EC_1 (e), EC_2 (f), and EC_3 (g) clusters. h Feature plots of the expression of selected marker genes for the EC subpopulations from the ND and HFD groups. i Violin plots of the expression of selected marker genes for the EC subpopulations from the ND and HFD groups. j Expression of cluster-specific and contractile genes for EC subpopulations as visualized by dot plot.