Table 2.
Analysis of association factors contributing to PBC.
| PBC rate (%) | Crude OR (95% CI) | Adjusted OR* (95% CI) | |
|---|---|---|---|
| Sphingomonadaceae deficient** | 13/31 (41.9) | 1.0 | 1.0 |
| Sphingomonadaceae rich** | 21/24 (87.5) | 9.69 (2.38–39.5) | 5.06 (1.05–24.3) |
| p value | 0.00153 | 0.0429 | |
| Pseudomonas deficient*** | 6/19 (31.6) | 1.0 | 1.0 |
| Pseudomonas rich*** | 28/36 (77.8) | 7.58 (2.18–16.4) | 6.7 (1.26–35.8) |
| p value | 0.00144 | 0.026 | |
| male | 2/11 (18.2) | 1.0 | 1.0 |
| female | 32/44 (72.7) | 12 (2.26–63.7) | 16 (1.76–146) |
| p value | 0.00353 | 0.0138 | |
| age | 1.0 (0.95–1.05) | 1.06 (0.98–1.15) | |
| p value | 0.96 | 0.12 | |
| ALP ****≦ 113 | 25/45 (55.5) | 1.0 | |
| ALP **** > 113 | 9/10 (90.0) | 7.2 (0.84–61.7) | |
| p value | 0.0716 |
*Logistic regression test was adjusted for covariates including gender and age.
**The cutoff values were 0.0000179.
***The cutoff values were 0.0000684.
****The cutoff value of ALP was set as the upper limit of normal, which is the diagnostic criterion for PBC.
PBC, primary biliary cholangitis; OR, odds ratio; CI, confidence interval; ALP, alkaline phosphatase.