Table 7.

Predicted multi-epitope based vaccines.

Vaccine name	Length	Vaccine constructs
Dengue virus vaccine-1 (DV-1)	352	GIINTLQKYYCRVRCAVLSCLPKEEQIGKCSTRGRKCCRRKKEAAAKAKFVAAWTLKAAAGGGSVVRPPFNMLKAAYLLFKTTEGINKAAYVTFKVPHAKAAYLMSAAIKDQKAAYKVASAGISYAAYATLKNVTEVKGGGSFLRVLSIPPTAGILKGPGPGNHGVTAMITPRSPSVGPGPGEQYKFQPESPARLASGPGPGAAIFMTATPPGATDPGPGPGLGKAYAQMWSLMYFHGGGSSIPPTAGILKRWGQLKKNKAKKYKCPLLVNTEPEDIDCWCNLKKITTATRCPTQGEPYLKEEQDKKLTPPVSDLKYSWKTWGKAKIKKNVTEVKGYTKGGPGHEEPIP
Dengue virus vaccine-2 (DV-2)	336	MAKLSTDELLKEMTLLELSDFVKKFEETFEVTAAAPVAVAAAGAAPAGAAVEAAEEQSEFDVILEAAGDKKIGVIKVVREIVSGLGLKEAKDLVDGAPKPLLEKVAKEAADEAKAKLEAAGATVTVKEAAAKAKFVAAWTLKAAAGGGSSIPPTAGILKAAYGTCTQSGERAAYMSYTMCSGKAAYHVQTKPGLFKAAYYVDYMPVMKGGGSKEIGRMLNILNGRKRGPGPGHGVTAMITPRSPSVEGPGPGAIFMTATPPGATDPFGPGPGTREEFISKVRSNAAIGGGSTLHWFRKGSSIGKMFESTYRKKTIIGRRLQRLQEEHKETWHY
Dengue virus vaccine-3 (DV-3)	336	MAENPNIDDLPLAALGAADLALATVNDLIANLRERAEETRAETRTRVEERRARLTKFQEDLPEQFIELRDKFTTEELRKAAEGYLEAATNRYNELVERGEAALQRLRSQTAFEDASARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLVGIELEAAAKAKFVAAWTLKAAAGGGSVAKHERGRPLLFKAAYVTFKVPHAKRAAYVQTKPGLFKAAYRGAVMDIISRKGGGSLRVLSIPPTAGILKRGPGPGHKQWFLDLPLPWTAGGPGPGKSGDYVSAITQAERIGPGPGCLGKAYAQMWSLMYFGGGSRGSSKIRWIVERGMVKPKGK
Dengue virus vaccine-4 (DV-4)	400	MSDINKLAENLKIVEVNDLAKILKEKYGLDPSANLAIPSLPKAEILDKSKEKTSFDLILKGAGSAKLTVVKRIKDLIGLGLKESKDLVDNVPKHLKKGLSKEEAESLKKQLEEVGAEVELKEAAAKAKFVAAWTLKAAAGGGSTTAKEVALLRAAYLTYQNKVVKAAYRSVSTETEKAAYKVDTRTPQPKAAYCTREEFISKAAYWSYYMATLKGGGSPFNMLKRERNRVSTPGPGPGFNMLKRERNRVSTPQGPGPGYKERMVTFKVPHAKRGPGPGKQWFLDLPLPWTAGAGPGPGSGDYVSAITQAERIGGPGPGTKSGDYVSAITQAERGPGPGPWDVIPMVTQLAMTDGPGPGACLGKAYAQMWSLMYGGGSDDTAGWDTRITEDDLQNEEL

The distinct bold sequences are the pan HLA DR-binding epitope (PADRE) while the B cell epitopes are italicized.