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. 2021 Oct 5;12(10):909. doi: 10.1038/s41419-021-04181-x

Table 2.

Commonly used cell lines in the translational models of prostate cancer.

Prostate cancer cell lines Source of cell Type of bone metastasis Androgen receptor (AR)+ Prostate-specific antigen (PSA)+ Reference
PC3 Bone Osteolytic [107110]
LNCaP Supraclavicular lymph node Osteoblastic + + [107, 109, 110]
LNCaP-C4-2B Subline of LNCaP Osteoblastic + [107, 108, 111115]
DU145 Brain Osteolytic [107, 109, 116118]