Fig. 6.

Late-life EOD fasting enhances hippocampal-dependent short-term memory. a Representative heatmap images of post-DI Y maze forced alternation task performance in the male Chow AL (left) and Chow EOD groups (right). b–e Number of arm entries at baseline in the male (b left) and female (d left) Chow AL and Chow EOD groups and post-DI in males (b right) and females (d right). Duration in each arm at baseline in the male (c left) and female (e left) Chow AL and Chow EOD groups and post-DI in males (c right) and females (e right). n = 5–7 mice per sex per group. The figures (a–e) depict the mean with error bars (± SEM). The asterisks indicate the significant difference between the same-sex Chow AL and Chow EOD groups. *p < 0.05 and **p < 0.01. The pound signs indicate the significant within group difference between the baseline and a post-DI time point. ^#p < 0.05. See also Supplemental Figure 6