Mean values ± SEM of main plasma FA, expressed as mol% respect to the total FAs, in octogenarians (> 80 years) from an area of Sardinia that possesses a strikingly high number of long-living people (Old-HLZ), subjects (65–70 years) from the same zone (Young-HLZ) and octogenarians (> 80 years) from a different area with a distinctly lower level of longevity (Old-LLZ). To assess the statistical significance amongst groups, we performed the Kruskal-Wallis test (one-way ANOVA on ranks) followed by Dunn’s correction for multiple comparisons. Different letters indicate significant differences amongst groups (p≤0.05). (FA, fatty acid; PA, palmitic acid; SA stearic acid; POA, palmitoleic acid; OA, oleic acid; ALA, alpha-linolenic acid; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; LA, linoleic acid; GLA, gamma-linolenic acid; ARA, arachidonic acid; CLA, conjugated linoleic acid; SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated acid)