Table 3.

Linear-mixed-model estimates of effect of left hemisphere cortical thickness, task, and moderation effect of cortical thickness-by-task on change in HbO₂, adjusted, FDR-corrected significant results

Region	Variable	Estimate	95% CI	t	p
Left cuneus	Thickness	− 1.363	[− 2.795, 0.069]	− 1.909	0.062
	Task (STW vs. DTW)	− 0.613	[− 0.703, − 0.523]	− 13.384	< 0.001
	Task × thickness	0.985	[0.271, 1.699]	2.706	0.007
Left fusiform	Thickness	− 1.310	[− 2.909, 0.290]	− 1.642	0.106
	Task (STW vs. DTW)	− 0.614	[− 0.704, − 0.525]	− 13.429	< 0.001
	Task × thickness	1.277	[0.470, 2.084]	3.105	0.002
Left inferior parietal	Thickness	− 1.436	[− 2.992, 0.119]	− 1.851	0.070
	Task (STW vs. DTW)	− 0.615	[− 0.705, − 0.525]	− 13.431	< 0.001
	Task × thickness	1.153	[0.382, 1.925]	2.931	0.003
Left isthmus cingulate	Thickness	− 1.141	[− 2.095, − 0.187]	− 2.399	0.020
	Task (STW vs. DTW)	− 0.614	[− 0.703, − 0.524]	− 13.421	< 0.001
	Task × thickness	0.834	[0.350, 1.319]	3.381	0.001
Left lateral occipital	Thickness	− 1.493	[− 2.864, − 0.122]	− 2.185	0.033
	Task (STW vs. DTW)	− 0.614	[− 0.703, − 0.525]	− 13.496	< 0.001
	Task × thickness	1.876	[1.202, 2.551]	5.454	< 0.001
Left lingual	Thickness	− 2.705	[− 4.516, − 0.893]	− 2.994	0.004
	Task (STW vs. DTW)	− 0.613	[− 0.702, − 0.523]	− 13.390	< 0.001
	Task × thickness	1.425	[0.549, 2.300]	3.191	0.001
Left pars orbitalis	Thickness	− 0.942	[− 2.195, 0.311]	− 1.508	0.137
	Task (STW vs. DTW)	− 0.613	[− 0.703, − 0.524]	− 13.389	< 0.001
	Task × thickness	0.767	[0.131, 1.404]	2.364	0.018
Left pericalcarine	Thickness	− 1.092	[− 2.893, 0.709]	− 1.216	0.229
	Task (STW vs. DTW)	− 0.613	[− 0.703, − 0.524]	− 13.432	< 0.001
	Task × thickness	1.847	[0.968, 2.727]	4.121	< 0.001
Left posterior cingulate	Thickness	− 1.242	[− 2.282, − 0.202]	− 2.395	0.020
	Task (STW vs. DTW)	− 0.615	[− 0.704, − 0.525]	− 13.434	< 0.001
	Task × thickness	0.891	[0.351, 1.430]	3.239	0.001
Left precuneus	Thickness	− 2.306	[− 3.880, − 0.733]	− 2.940	0.005
	Task (STW vs. DTW)	− 0.613	[− 0.703, − 0.523]	− 13.399	< 0.001
	Task × thickness	1.196	[0.423, 1.970]	3.034	0.002
Left rostral middle frontal	Thickness	− 1.617	[− 3.121, − 0.113]	− 2.155	0.036
	Task (STW vs. DTW)	− 0.614	[− 0.704, − 0.524]	− 13.411	< 0.001
	Task × thickness	1.186	[0.408, 1.964]	2.990	0.003
Left insula	Thickness	− 0.772	[− 1.949, 0.406]	− 1.314	0.194
	Task (STW vs. DTW)	− 0.614	[− 0.703, − 0.524]	− 13.416	< 0.001
	Task × thickness	0.930	[0.384, 1.477]	3.337	0.001

Only regions in which interaction effects remained significant after FDR correction are displayed. DTW is the reference group. Effect of channel, age, sex, GHS, RBANS, correct letter generation rate, and DTW velocity were included in each model

STW single-task walk, DTW dual-task walk