Table 1.
Molecular imprinted methods and their applications in bioimaging
| Template | Monomer | Crosslinker | Applications |
|---|---|---|---|
| Sialic acid (SA)-imprinted conjugated polymer nanoprobe | Poly(fluorene-alt-benzothiadiazole)- Phenylboronic acid (PFBT-PBA) | None | Targeting sialylated glycan levels using 2-photon fluorescent imaging [11] and cancer imaging [10] |
| Glucuronic acid (GlcA) | 4-Acetoxy-4′-acetylbiphenyl (AAB), methacrylamide (MAM) | Ethylene glycol dimethacrylate (EGDMA) | Imaging hyaluronan on cells and skin tissue [12] or targeting hyaluronan in HeLa cells [13] |
| N-Acetylneuraminic acid (NANA) and GlcA | MAM, 4′-acetylbiphenyl (AB) | EGDM | Imaging and labeling of hyaluronan and sialic acid [14] |
| l-Phenylalanin-amide | Methacrylic acid glacial (MAA) | EGDM | Studying the binding affinity between ligands and receptors [15] |
| Epidermal growth factor receptor (EGFR) | N-Isopropylacrylamide (NIPAAm) | None | Targeting living cells [16] |
| SA, Fucose (Fuc), Mannose (Man) | Fluorescent polymerization-based amplification (FPBA), tetraethoxysilane (TEOS) | Targeting and imaging of cancer cells [17] |