Table 3.

Applications of MI in biomedical fields

MI with improved material functions	Polymers	Template	Applications
Insulin- imprinted polymer	Mixture of methacrylic acid and N-hydroxyethyl acrylamide	Insulin	Reducing insulin release especially when taking insulin orally [55]
DOX-imprinted polymer	Mesoporous silica nanoparticles	DOX	Improvement in efficacy and release of the drug [63]
L-DOPA-imprinted polymer	β-Cyclodextrin and 1,1′-carbonyldiimidazole	L-DOPA	Enhanced prolonged release of the drug with an excellent clearance profile [67]
DFCR-imprinted polymer	Boronic acid	DFCR	Helps in the control released of the drug and increased selectivity to the target site [71]
5-Fluorouracil- imprinted polymer	Magnetic fluorescent core	5-fluorouracil	Increased efficacy of the drug 25 times than the drug alone [77]
Sunitinib-imprinting polymer	Fluorescent MIP	Sunitinib	Monitoring the drug fluorescently [75]
B family vitamin-imprinting polymers	Hydrophilic multi-template MI biopolymers (mt-MIBP) using chitosan as a bio-substance	Riboflavin, nicotinamide, and pyridoxine	Separation and determination of these vitamins in orange juice [78]
Bovine hemoglobin- imprinting with a fluorescence sensor	Tricolor-emission sensor that was constructed with a mixture of blue, green, and red- emission MIPs	Bovine hemoglobin	Detection and visualize of bovine hemoglobin [79]