Fig. 10.

Depletion of Nrip1 reduces p-p65 level in skin. a qRT-PCR verified the deletion of Nrip1 and examined the expression of p65, mTOR, and Igf1 in skin of Nrip1^+/+ and Nrip1^-/- mice. b Western blot quantification of p65 and p-p65 in skin of Nrip1^-/- and Nrip1^+/+ mice. c Immunohistochemical detection of p-p65 expression in young and old B6 mice, as well as in Nrip1^-/- and Nrip1^+/+ mice at old age (upper scale bar 100μm, down scale bar 50μm). *P<0.05, **P<0.01