Table 3.

Testosterone (ng/g) and estradiol (ng/g) content in the medial prefrontal cortex (MPFC) and striatum of aged male (n = 8) and female (n = 12) Tat-transgenic mice

	MPFC		Striatum
	Aged ♀	Aged ♂	Aged ♀	Aged ♂
Testosterone (mean, ng/g ± SD)	0.13 ± 0.14	1.04 ± 0.80*	0.08 ± 0.14	1.04 ± 0.94*
Estradiol (mean, ng/g ± SD)	0.019 ± 0.014	0.013 ± 0.024	0.024 ± 0.023	0.019 ± 0.018
Estradiol:testosterone ratio (mean ± SD)	27.0 ± 67.9	1.3 ± 1.7	11.0 ± 15.4	1.9 ± 2.0

*Greater than females, Student’s t-tests p = 0.001–0.002