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. 2021 Oct 6;37(3):109869. doi: 10.1016/j.celrep.2021.109869

Table 1.

Summary of various Nbs inhibiting pseudotyped SARS-CoV-2

Nbs IC50 (mean ± SD μg/ml) IC80 (mean ± SD μg/ml) IC90 (mean ± SD μg/ml)
1 × Nb15 0.3074 ± 0.0237 0.5059 ± 0.0699 0.622 ± 0.0969
2 × Nb15 0.0003 ± 0 0.0008 ± 0.0001 0.0011 ± 0.0001
3 × Nb15 0.0004 ± 0 0.001 ± 0 0.0014 ± 0.0001
4 × Nb15 0.0002 ± 0.0001 0.0008 ± 0.0001 0.0011 ± 0.0002
Nb15-NbH 0.5529 ± 0.0889 1.071 ± 0.1754 1.374 ± 0.2263
NbH-Nb15 0.1974 ± 0.004 0.3469 ± 0.0533 0.4344 ± 0.0822
Nb15-Nb15-NbH 0.0251 ± 0.0058 0.0419 ± 0.0051 0.0517 ± 0.0047
NbH-Nb15-Nb15 0.0008 ± 0.0001 0.0017 ± 0.0003 0.0022 ± 0.0004
Nb15-NbH-Nb15 0.0004 ± 0 0.0009 ± 0 0.0013 ± 0
Nb15-Fc 0.0009 ± 0.0001 0.0019 ± 0.0001 0.0025 ± 0.0002