TABLE 2.

Aptamer in clinical trials.

Name	Disease	Target	ClinicalTrials.gov Identifier	Recruitment Status	Phase	Reference
Zimura	Macular Degeneration	C5	NCT02686658	Completed	II/III	Jaffe et al. (2020)
Pegcetacoplan	Geographic atrophy	C3	NCT02503332	Completed	II	Liao et al. (2020)
E10030	Macular Degeneration	PDGF	NCT00569140	Completed	I	Jaffe et al. (2016)
E10030	Macular Degeneration	PDGF	NCT01089517	Completed	II	Jaffe et al. (2017)
ARC1779	von Willebrand Disease	von Willebrand Factor (vWF) A1	NCT00432770	Completed	I	Gilbert et al. (2007)
NOX-H94	Anemia of Chronic Disease	Hepcidin	NCT01691040	Completed	II	Georgiev et al. (2014)
NOX-E36	Type 2 Diabetes Mellitus, Albuminuria	C-C motif-ligand 2	NCT01547897	Completed	II	Menne et al. (2017)