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Clinically approved RNA therapeutics.
| Drug | Molecule | Target | Disease | Reference |
|---|---|---|---|---|
| mRNA-1273 | mRNA | Spike (S) protein of SARS-CoV-2 | COVID-19 | USFDA, (2021a) |
| BNT162b1 | RBD of Spike glycoprotein | USFDA, (2021b) | ||
| Patisiran | siRNA | Polyneuropathy | Hereditary transthyretin-mediated amyloidosis | Adams et al. (2018) |
| Givosiran | siRNA | ALAS1 | AHP | USFDA, (2019) |
| Pegaptanib | Aptamer | VEGF | AMD | Vinores, (2006) |
