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. 2021 Oct 1;54(3):350–360. doi: 10.5115/acb.20.299

Fig. 7.

Fig. 7

Total lesion volume after SCI: ibrutinib administration significantly diminished the lesion volume four weeks after SCI. Cavities (arrows) and the surrounding spared tissue were measured in the different groups by Cavalieri᾽s principle. (A) Sham, (B) Control, (C) Ibrutinib/Immediate, (D) Ibrutinib/12-hour, (E) Ibrutinib/double injection. (F) Graph showing total lesion volume in different treatment groups. Cresyl violet staining; magnification: 90×. aP<0.001 vs. control, bP<0.001 vs. other groups.