Table 1.
Characteristics of pMMR CRC patients who received neoadjuvant chemotherapy (NCT) or did not receive NCT (non-NCT) (n = 77).
| Clinicopathological parameters | Non-NCT (n = 39) | NCT (n = 38) | P value |
|---|---|---|---|
| n (%) | n (%) | ||
| Age (years) | 0.307 | ||
| ≤ 60 | 23 (59) | 18 (47.4) | |
| > 60 | 16 (41) | 20 (52.6) | |
| Tumor sizea (cm) | 0.226 | ||
| ≤ 4 | 26 (66.7) | 30 (78.9) | |
| > 4 | 13 (33.3) | 8 (21.1) | |
| Gender | 0.162 | ||
| Male | 24 (62) | 29 (76) | |
| Female | 15 (38) | 9 (24) | |
| LVIa | 0.591 | ||
| Negative | 31 (79.5) | 32 (84.2) | |
| Positive | 8 (20.5) | 6 (15.8) | |
| PNIa | 0.680 | ||
| Negative | 36 (92.3) | 33 (86.8) | |
| Positive | 3 (7.7) | 5 (13.2) | |
| Tumor differentiationa | 0.209 | ||
| Poor/Moderate | 27 (69.2) | 31 (81.6) | |
| Well | 12 (30.8) | 7 (18.4) | |
| cTb | 0.573 | ||
| cT3 | 22 (56.4) | 19 (50) | |
| cT4 | 17 (43.6) | 19 (50) | |
| cNb | 0.570 | ||
| cN0 | 21 (53.8) | 18 (47.4) | |
| cN+ | 18 (46.2) | 20 (52.6) | |
| cTNMb | 0.570 | ||
| II | 21 (53.8) | 18 (47.4) | |
| III | 18 (46.2) | 20 (52.6) |
a
Based on the pathological diagnose.
b
Based on the clinical imaging assessments.
LVI, Lymphovascular invasion. PNI, Perineural invasion.