TABLE 3.

Comparison of Health Assessment Questionnaire-Disability Index (HAQ-DI) scores between and within the study groups.

HAQ-DI score	Metformin group n = 30	Control group n = 30	p-value
Baseline, median (range)	2.13 (0.63–2.5)	2 (1.25–2.63)	1b
After 3 months, median (range)	1.88 (0.38–2.38)	2.13 (1.25–2.50)	0.006a , b
After 6 months, median (range)	1.56 (0.38–2.25)	2.13 (1.75–2.50)	<0.001a , b
p-value	<0.001a , c , d	0.065c

^aIndicates statistical significance (p-value <0.05).

^bMann-Whitney test.

^cFriedman test.

^dPost-hoc tests (pairwise comparisons) revealed significance differences in HAQ between baseline-after 3 months, and baseline-after 6 months.