TABLE 1.

Concentrations of four serum tumor markers.

Serum tumor markers	Benign SPNs group (n = 300)	Malignant SPNs group (n = 300)	Z	p
NSE (ng/ml)	12.11 (11.49, 12.59)	14.83 (12.56, 16.17)	−9.896	<0.001
CYFRA21-1 (ng/ml)	2.16 (1.99, 2.30)	6.77 (4.75, 7.84)	−17.627	<0.001
CA125 (U/mL)	18.42 (14.95, 21.08)	46.30 (36.05, 54.05)	−16.653	<0.001
CA153 (U/mL)	10.37 (9.39, 11.33)	17.77 (14.49, 19.64)	−13.258	<0.001