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Analysis of six of the top upregulated genes in the blood of breast cancer patients with subclinical DOX-induced cardiotoxicity [115] using HeartBioportal database: (A) MPO; (B) MMP9; (C) CEACAM8; (D) CAMP; (E) PGLYRP1; (F) ELANE. The elevated expression of the six genes after the initial DOX dose in patients with abnormally decline LVEF correlate with upregulation in cardiovascular diseases.
