Table 2.
Clinical overview of BORSA cases involved in 2014–2016 outbreak analysis
|
Patient |
Year |
Medical history |
BORSA infection |
Antibiotic pretreatment |
|---|---|---|---|---|
|
P1: F, 52y |
2014 |
Keratosis follicularis |
Cellulitis of both ears with alternating BORSA-positive cultures and chronic BORSA carrier |
Flucloxacillin oral course |
|
P2: M, 76y |
2015 |
Recurrent squamous cell carcinoma |
Infection of wound after excision of skin carcinoma |
Cotrimoxazol oral course. Fusidic acid topical course |
|
P3: F, 46y |
2016 |
Acute undifferentiated leukaemia, 6 months after SCT, GvHD skin |
Cellulitis, secondary infecion of GvHD of the skin, small abscess of the axilla |
Cotrimoxazol oral course |
|
P4: M, 27y |
2016 |
Eczema, aortic prosthetic valve due to congenital heart disease |
Recurrent MSSA endocarditis with involvement of prosthetic material. Patient was initially treated with high-dose flucloxacillin and during the fourth episode of recurrence a BORSA was identified and treatment switched to vancomycin after 5 days. Fatal outcome |
Three high-dose flucloxacillin i.v. courses of 6–8 weeks followed by oral clindamycin |
|
P5; F, 58y |
2016 |
Psoriasis, SLE, diabetic foot |
Infected ulcers on the foot, cellulitis |
Flucloxacillin and clindamycin oral course |
|
P6: M, 22y |
2016 |
Eczema |
Infected eczema |
No pre-treatment |
|
P7: M, 79y |
2016 |
Late-onset eczema |
Ecthyma form of impetigo located on the hand |
No pre-treatment |
|
P8: M, 23Y |
2015 |
Kidney transplantation |
S. aureus bacteraemia and possible endocarditis originating from an infected venous line, complete recovery |
Unkown |
Year, most recent year with positive cultures available; antibiotic pretreatment, antibiotics received in the year prior to BORSA infection; F, female; M, male; y, years; SCT, stem cell transplantation; GvHD, graft versus host disease; SLE, systemic lupus erythematosis.