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. 2021 Oct 5;4(10):e2125166. doi: 10.1001/jamanetworkopen.2021.25166

Table 3. Baseline Values of Total and Regional WMH Volumes and of Rates of Cortical Thinning of Clusters Associated With WMH, by Racial and Ethnic Group.

Measure Participants, mean (SD) F P value
White Hispanic Non-Hispanic Black
WMH, cm3
Total 4.54 (5.62) 4.35 (4.88) 5.43 (5.49) 1.032 .36
Frontal 1.91 (2.70) 1.86 (2.46) 2.32 (3.10) 0.709 .49
Temporal 0.35 (0.54) 0.23 (0.32) 0.35 (0.46) 1.186 .31
Parietal 1.16 (2.14) 1.13 (1.84) 1.55 (1.90) 1.369 .26
Occipital 0.47 (0.56) 0.34 (0.38) 0.39 (0.50) 1.754 .18
SPC, total WMH
Right caudal middle frontal −0.12 (0.93) −0.24 (0.75) −0.19 (1.50) 0.943 .39
Right paracentral −0.46 (1.44) −0.14 (1.67) −0.58 (2.35) 0.371 .69
SPC, parietal WMH
Right rostral middle frontal −0.11 (0.85) −0.18 (0.77) −0.25 (1.47) 1.630 .20
Right pars triangularis −0.13 (0.63) −0.13 (0.83) −0.40 (1.46) 3.434 .03
Right paracentral −0.48 (1.36) −0.14 (1.61) −0.59 (2.13) 0.428 .65
Left entorhinal −0.60 (1.09) −0.62 (1.10) −0.49 (1.36) 0.166 .85

Abbreviations: SPC, symmetrized percent change; WMH, white matter hyperintensities.