Comparison 4. Acceptance interventions for weight concern.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
4.1 Mean weight change (kg) at end of treatment	3		Mean Difference (IV, Random, 95% CI)	Totals not selected
4.1.1 Acceptance intervention, no additional pharmacotherapy	2		Mean Difference (IV, Random, 95% CI)	Totals not selected
4.1.2 Acceptance intervention, with bupropion in both arms	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
4.1.3 Acceptance intervention, with NRT in both arms	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
4.2 Mean weight change (kg) at 6 months	3	106	Mean Difference (IV, Random, 95% CI)	‐0.00 [‐1.53, 1.53]
4.2.1 CBT to accept moderate weight gain versus no behavioural weight advice, no additional pharmacotherapy	2	55	Mean Difference (IV, Random, 95% CI)	‐1.05 [‐5.55, 3.45]
4.2.2 CBT to accept moderate weight gain versus no behavioural weight advice, with bupropion	1	46	Mean Difference (IV, Random, 95% CI)	0.86 [0.30, 1.42]
4.2.3 Acceptance intervention versus health education, with NRT	1	5	Mean Difference (IV, Random, 95% CI)	‐0.53 [‐5.72, 4.66]
4.3 Mean weight change (kg) at 12 months	2	76	Mean Difference (IV, Random, 95% CI)	‐0.70 [‐2.95, 1.56]
4.3.1 CBT to accept moderate weight gain versus no behavioural weight advice, no additional pharmacotherapy	2	44	Mean Difference (IV, Random, 95% CI)	‐2.15 [‐7.54, 3.24]
4.3.2 CBT to accept moderate weight gain versus no behavioural weight advice, with bupropion	1	32	Mean Difference (IV, Random, 95% CI)	0.38 [‐0.57, 1.33]
4.4 Smoking cessation at 6 months	4	619	Risk Ratio (M‐H, Random, 95% CI)	1.42 [1.03, 1.96]
4.4.1 CBT to accept moderate weight gain versus no behavioural weight advice (no additional pharmacotherapy)	3	355	Risk Ratio (M‐H, Random, 95% CI)	1.53 [0.92, 2.55]
4.4.2 CBT to accept moderate weight gain versus no behavioural weight advice (with bupropion)	1	195	Risk Ratio (M‐H, Random, 95% CI)	1.36 [0.85, 2.16]
4.4.3 ACT for weight concern versus health education	1	69	Risk Ratio (M‐H, Random, 95% CI)	0.73 [0.22, 2.35]
4.5 Smoking cessation at 12 months	2	496	Risk Ratio (M‐H, Random, 95% CI)	1.25 [0.76, 2.06]
4.5.1 CBT to accept moderate weight gain versus no behavioural weight advice (no additional pharmacotherapy)	2	301	Risk Ratio (M‐H, Random, 95% CI)	1.45 [0.58, 3.59]
4.5.2 CBT to accept moderate weight gain versus no behavioural weight advice (with bupropion)	1	195	Risk Ratio (M‐H, Random, 95% CI)	1.06 [0.62, 1.81]