Table 2.

Effect of MDSC on T cell production of 27 Innate Cytokines, under differing stimulation combinations (Unstimulated and anti-CD3CD28 beads), measured by Luminex. Data analysed by Mixed Model, LS means and Type III decomposition using Statistica (Quest Software, Elliot Management Group). A p-value less than 0.05 was considered significant.

Analytes	T cell vs T cell co-cultured with MDSC
	Unstim (p-value)	Significant Increase/Decrease/ns	aCD3CD28 (p-value)	Significant Increase/Decrease/ns
IL1b	0.136537	ns	0.020006	n/a
IL1ra	0.000006	n/a	0	n/a
IL2	0.467837	ns	0.000074	decrease
IL4	0	n/a	0.000086	decrease
IL6	0	n/a	0.000001	n/a
IL7	0	n/a	0.017214	n/a
IL9	0.000009	n/a	0.669309	ns
IL10	0	n/a	0.944703	ns
IL12	0.110671	ns	0.436979	ns
IL13	0.000603	n/a	0.041371	decrease
IL15	0	n/a	0	n/a
IL17A	0	n/a	0.855873	ns
FGF basic	0.000033	n/a	0.19259	ns
IFNg	0.89317	ns	0.878242	ns
MCP1	0	n/a	0	n/a
MIP1a	0.000016	n/a	0.144661	ns
PDGF-bb	0	n/a	0.00032	n/a
MIP1b	0	n/a	0.552896	ns
TNFa	0	n/a	0.031027	n/a
IL5	0	n/a	0.69174	ns
IL8	0	n/a	0	n/a
Eotaxin	0	n/a	0.425538	ns
G-CSF	0.000003	n/a	0.923801	ns
IP10	0	n/a	0.000001	n/a
RANTES	0	n/a	0.193398	ns
GM-CSF	0.031863	n/a	0.011171	decrease
VEGF	0	n/a	0.086424	ns