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. Author manuscript; available in PMC: 2022 Apr 21.
Published in final edited form as: J Bone Joint Surg Am. 2021 Apr 21;103(8):705–714. doi: 10.2106/JBJS.20.00696

TABLE VI.

Summary of Major Previous Reports on Rotating-Hinge Knee Replacement in Bone Tumor Surgery*

Revision Rate Per Failure Type
Report Institution No. of DFR
Cases
Prosthesis Follow-up (yr) Type 1 Type 2 Type 3 Type 4 Type 5 Implant Survival/Cumulative
Incidence of Failure
Analysis
Pala et al.9, CORR, 2015 Instituto Rizzoli 187 GMRS (Stryker) Mean, 4 (range, 2-8) 8.5% 5.7% NR 9.3% 5.7% Implant survival, 73% and 60% at 4 and 8 yr Kaplan-Meier; RH followed max. 8 yr
Pala et al.18, Int Orthop, 2016 Instituto Rizzoli RH, 196 GMRS (Stryker) Mean, 7.9 (range, 0-27) 6.1% 2.0% NR 6.6% 4.6% Kaplan-Meier; mixture of femoral/tibial cases; mixture of RH/FH; RH followed max. 7 yr
Myers et al.8, JBJS Br, 2007 Royal Orthopaedic Hospital RH, 174; FH, 161 Custom (Stanmore) Unknown for RH; mean, 12 (range, 5-30) for RH and FH survivors NR NR NR NR NR Cumulative incidence of failure for RH, 17% and 22% at 5 and 10 yr Kaplan-Meier; mixture of RH/FH; RH followed max. 12 yr
Bickels et al.4, CORR, 2002 George Washington University and Tel-Aviv University 102 Custom and modular (Howmedica) Median, 7.8 (range, 2-16.5) NR 5.4% NR 5.4% NR Implant survival, 93% and 88% at 5 and 10 yr Kaplan-Meier; most cases censored at <5 yr
Morgan et al.7, CORR, 2006 University of Washington 76 Modular (several manufacturers) Median 4.8 (range, 0.1-19.6) NR 17.1% NR 41.9% NR Implant survival, 73% and 59% at 5 and 10 yr Kaplan-Meier; most cases censored at <5 yr
Coathup et al.5, JBJS, 2013 Royal National Orthopaedic Hospital 61 Custom (Stanmore) Mean, 8.5 (range, 2-16) NR 8.0% 3.0% 3.0% 5.0% Implant survival, 75%, 84%, and 89% at 5, 10, and 15 yr Kaplan-Meier; most cases censored at <5 yr
Batta et al.2, BJJ, 2014 Royal National Orthopaedic Hospital 69 Custom (Stanmore) Mean, 10.4 (range, 0.3-17.7) 7.0% 13.0% 10.0% 7.0% 4.0% Implant survival, 73%, 65%, and 55% at 5, 10, and 15 yr Kaplan-Meier; most cases censored at <5 yr
Schwartz et al.10, CORR, 2010 UCLA 186 Custom, 54; GMRS, 46% (several manufacturers) Mean, 8.0 (range, 0.1-28.0) NR 29.0% NR 3.2% NR Implant survival, 77% at 10 yr (survival without revision) Kaplan-Meier; several different prostheses; most cases censored at <5 yr
Bus et al.1, CORR, 2017 Leiden University 89 MUTARS (implantcast) Mean, 7.2 (range, 0.4-18) 6.0% 16.0% 14.0% 13.0% 10.0% Cumulative incidence of failure, 30%, 37%, and 54% at 5, 10, and 15 yr Competing risk analysis; several different prostheses; most cases censored at <5 yr
Current study MSK 214 Finn/OSS (Biomet) Mean, 12.4 for survivors (9.1 overall) 0% 15.0% 10.7% 10.3% 1.4% Cumulative incidence of failure, 22.6%, 30.1%, 34.4%, and 42.5% at 5, 10, 15, and 20 yr Competing risk analysis; no mixture of RH/FH; no mixture of femoral/tibial cases; used single prosthesis (Finn/OSS)
*

DFR = distal femoral replacement, GMRS = Global Modular Replacement System, NR = not reported, RH = rotating hinge, FH = fixed hinge, UCLA = University of California Los Angeles, MUTARS = Modular Universal Tumor And Revision System, MSK = Memorial Sloan Kettering Cancer Center, and OSS = Orthopaedic Salvage System.