Table 2.

Cardiovascular defects in Pax9:Msx1 mutant embryos at E12.5

Genotype	n	Absent 3rd PAA	Absent 4th PAA
Control	2	0/4	0/4
CD1-Pax9–/–	4	7/8	8/8
CD1-Pax9–/–;Msx1+/–	6a	4/12*	5/12*

Embryos were assessed by μCT and the 3rd and 4th PAAs (i.e. two of each per embryo) scored for being absent in each genotype. PAA defects in CD1-Pax9^–/–;Msx1^+/– embryos were significantly reduced when compared to CD1-Pax9^–/– embryos

PAA pharyngeal arch artery

*p < 0.05 (Fisher’s exact test for associations)

^aTwo embryos were normal with no PAA defects