Table 2. A summary of inferred parameter values from the mathematical IKr model.
| WT | WT + RPR | R56Q | R56Q + RPR | ||
|---|---|---|---|---|---|
| p1 | 8.53E-03 | 6.67E-03 | 6.49E-03 | 7.66E-03 | |
| p2 | 8.32E-02 | 7.52E-02 | 6.97E-02 | 6.99E-02 | |
| p3 | 1.26E-02 | 2.71E-04 | 7.35E-03 | 1.44E-03 | |
| p4 | 1.04E-07 | 2.44E-02 | 1.49E-07 | 1.43E-02 | |
| p5 | 2.70E-01 | 1.72E-01 | 2.44E-01 | 1.48E-01 | |
| p6 | 1.58E-02 | 2.18E-02 | 2.18E-02 | 2.76E-02 | |
| p7 | 7.67E-02 | 7.12E-02 | 8.10E-02 | 8.74E-02 | |
| p8 | 2.25E-02 | 3.13E-02 | 1.98E-02 | 3.26E-02 | |
| p9 | 1.49E-01 | 6.21E+02 | 2.04E-01 | 1.19E-01 | |
| p10 | 2.43E-02 | 7.81E-03 | 6.74E-02 | 5.30E-03 | |
| p11 | 5.58E-04 | 2.10E+02 | 6.73E-03 | 8.60E-02 | |
| p12 | 4.07E-02 | 5.03E-04 | 2.94E-02 | 7.98E-03 | |
| Cell 1 | 8.47E-02 | 7.96E-02 | |||
| G Kr | Cell 2 | 7.05E-02 | 1.03E-01 | ||
| Cell 3 | 1.23E-01 | 4.33E-02 | |||
Parameters p1, p3, p5, p7, p9, and p11 have units of ms−1, parameters p2, p4, p6, p8, p10, p12 have units of mV−1, and the maximal conductance parameters, GKr, have units of μS.